CHINA Developing SECRET influenza VIRUS
Experts warn of danger
that the new viral strains created by mixing bird-flu virus with human
influenza could escape from the laboratory to cause a global pandemic
killing millions of people.
Senior scientists have
criticised the "appalling irresponsibility" of researchers in China who
have deliberately created new strains of influenza virus in a veterinary
laboratory.
They warned there is a danger that the new viral
strains created by mixing bird-flu virus with human influenza could
escape from the laboratory to cause a global pandemic killing millions
of people.
Lord May of Oxford, a former government chief
scientist and past president of the Royal Society, denounced the study
published today in the journal Science as doing nothing to further the
understanding and prevention of flu pandemics.
"They claim they
are doing this to help develop vaccines and such like. In fact the real
reason is that they are driven by blind ambition with no common sense
whatsoever," Lord May told The Independent.
"The record of
containment in labs like this is not reassuring. They are taking it upon
themselves to create human-to-human transmission of very dangerous
viruses. It's appallingly irresponsible," he said.
The
controversial study into viral mixing was carried out by a team led by
Professor Hualan Chen, director of China's National Avian Influenza
Reference Laboratory at Harbin Veterinary Research Institute.
Professor
Chen and her colleagues deliberately mixed the H5N1 bird-flu virus,
which is highly lethal but not easily transmitted between people, with a
2009 strain of H1N1 flu virus, which is very infectious to humans.
When
flu viruses come together by infecting the same cell they can swap
genetic material and produce "hybrids" through the re-assortment of
genes. The researchers were trying to emulate what happens in nature
when animals such as pigs are co-infected with two different strains of
virus, Professor Chen said.
"The studies demonstrated that H5N1
viruses have the potential to acquire mammalian transmissibility by
re-assortment with the human influenza viruses," Professor Chen said in
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"This tells us that high attention should be
paid to monitor the emergence of such mammalian-transmissible virus in
nature to prevent a possible pandemic caused by H5N1 virus," she said.
"It
is difficult to say how easy this will happen, but since the H5N1 and
2009/H1N1 viruses are widely existing in nature, they may have a chance
to re-assort," she added.
The study, which was carried out in a
laboratory with the second highest security level to prevent accidental
escape, resulted in 127 different viral hybrids between H5N1 and H1N1,
five of which were able to pass by airborne transmission between
laboratory guinea pigs.
Professor Simon Wain-Hobson, an eminent
virologist at the Pasteur Institute in Paris, said it is very likely
that some or all of these hybrids could pass easily between humans and
possess some or all of the highly lethal characteristics of H5N1
bird-flu.
"Nobody can extrapolate to humans except to conclude
that the five viruses would probably transmit reasonable well between
humans," Professor Wain-Hobson said.
There is no evidence that
the deadly H7N9 bird flu has yet spread between humans in China but
health authorities must be ready for the virus to mutate at any time, a
top US virologist has warned.
Anthony Fauci, the head of the
National Institute of Allergy and Infectious Diseases (NIAID), said
officials in China had studied more than 1,000 close contacts of
confirmed cases and not found any evidence of human-to-human
transmission.
"That is powerful evidence because if you had a
thousand contacts with someone with the flu you would be pretty sure
some of them would have been infected," Fauci said in an interview with
AFP.
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